1,945 research outputs found

    Active control system trends

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    The active control concepts which achieve the benefit of improved mission performance and lower cost and generate system trends towards improved dynamic performance, more integration, and digital fly by wire mechanization are described. Analytical issues and implementation requirements and tools and approaches developed to address the analytical and implementation issues are briefly discussed

    Spaceborne memory organization, an associative data acquisition system, phase II Final report, Apr. - Dec. 1966

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    Spaceborne memory organization, associative data acquisition system design, and data compression technique

    Spaceborne memory organization, phase 1 Final report

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    Application of associative memories to data processing for future space vehicle

    Spaceborne memory organization Interim report

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    Associative memory applications in unmanned space vehicle

    Identifying Abnormal Returns to Food and Agribusiness Stocks on Key Farm Policy Legislative Dates

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    The efficient market hypothesis would suggest that stock prices incorporate the information revealed in the public process of creating legislation as the debate occurred. Thus, there should be no abnormal returns to agribusiness stocks on key legislative dates when drafting and altering the farm bill. Using an event study methodology, key legislative dates are tested for abnormal returns to firms that supply inputs to or process outputs of agricultural producers. Typically, agribusinesses react on the date legislation emerges from the joint House and Senate conference committee.agribusiness stock values, event study, farm bill, Agribusiness, Agricultural and Food Policy,

    Protecting Your Turf: First-mover Advantages as a Barrier to Competitor Innovation

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    Product innovation for a juice company and its associated first-mover advantages are analyzed. Stochastic simulation is used to model market size, price, competitive intensity, and the likelihood of competitor entry. Results of moving first allow the firm to capture market share, realize first-mover advantages in excess of $2 million, and deter competitor innovation. In addition, the proposed model is flexible enough to be applied in other industries.Product innovation, first-mover advantages, barriers to entry, stochastic simulation, uncertainty, Research and Development/Tech Change/Emerging Technologies,

    Spontaneous Scalarization and Boson Stars

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    We study spontaneous scalarization in Scalar-Tensor boson stars. We find that scalarization does not occur in stars whose bosons have no self-interaction. We introduce a quartic self-interaction term into the boson Lagrangian and show that when this term is large, scalarization does occur. Strong self-interaction leads to a large value of the compactness (or sensitivity) of the boson star, a necessary condition for scalarization to occur, and we derive an analytical expression for computing the sensitivity of a boson star in Brans-Dicke theory from its mass and particle number. Next we comment on how one can use the sensitivity of a star in any Scalar-Tensor theory to determine how its mass changes when it undergoes gravitational evolution. Finally, in the Appendix, we derive the most general form of the boson wavefunction that minimises the energy of the star when the bosons carry a U(1) charge.Comment: 23 pages, 5 postscript figures. Typing errors corrected. Includes some new text that relates the paper to several previous results. Accepted for publication in PR

    TGFβ1 Overexpression by Keratinocytes Alters Skin Dendritic Cell Homeostasis and Enhances Contact Hypersensitivity

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    Overexpression of transforming growth factor beta-1 (TGFβ1) in mouse epidermis causes cutaneous inflammation and keratinocyte hyperproliferation. Here we examined acute effects of TGFβ1 overproduction by keratinocytes on skin dendritic cells (DCs). TGFβ1 induction for 2 and 4 days increased the numbers and CD86 expression of B220+ plasmacytoid DCs (pDCs) and CD207+CD103+, CD207−CD103−CD11b+, and CD207−CD103−CD11b− dermal DCs (dDCs) in skin-draining lymph nodes (SDLNs). The dermis of TGFβ1-overexpressing mice had significantly more pDCs, CD207+CD103+ dDCs, and CD207−CD11b+ dDCs in the absence of increased dermal proliferation. Application of dye, tetramethyl rhodamine iso-thiocyanate (TRITC), in dibutylpthalate (DBP) solution after TGFβ1 induction increased the numbers of TRITC+CD207− dDCs in SDLNs, and augmented TRITC/DBP-induced Langerhans cell (LC) migration 72hours post TRITC treatment. Consistent with this, LC migration was increased in vitro by TGFβ1 overexpression in skin explants and by exogenous TGFβ1 in culture media. Transient TGFβ1 induction during DNFB sensitization increased contact hypersensitivity responses by 1.5-fold. Thus, elevated epidermal TGFβ1 alone is sufficient to alter homeostasis of multiple cutaneous DC subsets, and enhance DC migration and immune responses to contact sensitizers. These results highlight a role for keratinocyte-derived TGFβ1 in DC trafficking and in the initiation of skin inflammation
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